BREAST CANCER ACTIVITY OF ISOLATED COMPOUND FROM TINOSPORA CORDIFOLIA AERIAL
نویسندگان
چکیده
Objectives: The present study undertaken to explore antioxidant and the cell line of isolated compound from ethanol extract Tinospora cordifolia belongs family Menispermaceae.
 Methods: air dried powdered sample aerial parts T. was extracted in a Soxhlet using five different solvents. Most active extracts were purified silica gel column chromatography. Characterized structure Fourier transform infrared spectrum, 1H nuclear magnetic resonance, liquid chromatography–mass spectrometry studies. Antioxidant anticancer activity determined 2,2-diphenyl-1-picrylhydrazyl 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.
 Results: Magnoflorine most which shows maximum 64% at tested concentration 500 μg/ml. percentage viability varied 53.3% minimum 3.12 μg/ml 1.9% 100 μg/ml.
 Conclusion: characterized compounds would be useful prepare plant-based pharmaceutical preparation treat various diseases linked with human diseases.
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2021
ISSN: ['0974-2441', '2455-3891']
DOI: https://doi.org/10.22159/ajpcr.2021.v14i3.39706